Results 1 – 9 of 9 BIOSTATISTIQUE by SCHERRER BRUNO and a great selection of related books , art and collectibles available now at : BIOSTATISTIQUE: IN 8 relié en bon état, pages, ( légères traces de noircissement ou de jaunissement sur le dos et le second plat, . Biostatistique by Bruno Scherrer. (Paperback ).

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The intensity of Group 2 artifact ranged from 1. Shape regularity was assumed true only for Group 3 and thus, whenever used, the regional potential was calculated considering Group 3 membership vs. Today, voxel intensity analyses seem to be insufficient. For this, the non-spatial lesion-segmentation algorithm was applied to Patients 1—4. Misclassified tissue volumes in Alzheimer disease patients with white matter hyperintensities: First, estimation of the spatial prior defined by 3.

Determination of glutathione and glutathione disulfide in biological samples. Polyamine metabolism in sunflower plants under long-terme cadmium or copper stress. International Journal of Ecotoxicology and Ecobiology. Application to segmentation of stroke lesions. We tested the robustness of the segmentation model to noise, linear artifacts, and spherical artifacts.

Software is available upon request. The phylogenetic characterisation of all 47 French EBLV-1 isolates sampled between and and the French BBLV sample against 21 referenced partial nucleoprotein sequences confirmed the low genetic diversity of EBLV-1 despite its extensive geographical range.

The regional regularization was less efficient because of a more important edge effect. Application to microbiome count data. Oasis is automated statistical inference for segmentation, with applications to multiple sclerosis lesion segmentation in MRI. Indeed, important artifacts are frequently present in MRI brain scans of elderly patients with history of white matter disease WMD Manolio and othersand lead to poor segmentation with tortuous lesion shapes and high false-positive rates.


Mixture models with adaptive spatial regularization for segmentation with an application to FMRI data. Variational EM algorithm maximizes sequentially the lower approximation of the log-likelihood called lower bound under the factorization constraint.

Acute biochemical responses of a submersed macrophyte, Potamogeton crispus L.

Latest Most Read Most Cited Estimation of high-dimensional directed acyclic graphs with surrogate intervention. This is why a spatial correlation between neighboring sites is integrated into the fMM to model the spatial homogeneity of the groups. Free University of Bozen – Bolzano It ranges between 0 perfect agreement between observation and prediction and 1 complete discrepancy.

Biostatistique T.01 2e éd.

Next, the robustness against linear artifacts was scherrer by incorporating into Group 2 and Group 3 a 2-pixels-wide linear artifact Dataset 2. Because it is a weighted sum of concave functions, it ensures the uniqueness of the maximum. Local and regional potentials for geometric forms and for an example of stroke lesion.

Because artifacts concern only a few sites, bad performance for these sites might not be detected by global performance measures. The use of spatial information together with intensity analysis becomes then necessary. Imaging data were acquired with a 1. Determination of protein bound scerrer in serum by a modified anthrone method.

Group 1 and 2 membership.

Bruno Scherrer (Author of Biostatistique)

The potentials range from 0 [light gray biosttaistique color in online ] to 1 [dark gray red color in biostatistuque ]. The probability distribution common to the local and the regional regularization corresponds to a particular Gibbs distribution where the spatial dependencies are restricted to pairs of sites and where the neighborhood system and the potential form are specified.

We tested 5 specifications of the fMM: En savoir plus Enregistrer dans les favoris. Every year, more than scientists from Switzerland and other countries travel to PSI in order to perform experiments at our unique facilities.

Pereyra and othersbut, to be applicable, they should be extended to the regional approach. By using the mean-field approximation, we obtained a pseudo-likelihood estimator which has good theoretical properties and was computationally efficient.

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We compared three mixture-model specifications: It is computed as the ratio of the estimated volume to the true volume. Springer Verlag, Berlin, p. Withdrawing this model led to close performances but with faster computations. University of Oulu On the other hand, imaging techniques offer now a multiparametric voxel characterization that may help differentiating lesioned from non-lesioned voxels.

For the stroke lesion, the potentials were computed with a 3D neighborhood. Effect of aluminium on lipid peroxidation, superoxide dismutase, catalase and peroxidase activities in root tips of soybean glycine max. PSI has about staff, with an annual budget of approximately CHF million, and is primarily financed by the Swiss Confederation.

Both methods tended to over-estimate the local regularization parameter and underestimate the regional regularization parameter. Ultimately, however, our employees — the brains behind the machines — are our major strength, as PSI’s most crucial capital resource is the outstanding competence, experience and motivation of its employees. It would be thus very useful to develop an automated classification algorithm able to identify lesion-related voxels.


Molecular mechanisms of quenching of reactive oxygen species by proline under stress in plants. Thus, for robustness against local optima, one should use several initializations and keep the best segmentation. Using an edge-preserving filter a Gaussian kernel weighted by the difference in intensity between the site and its neighbors gave satisfactory results in patients with intensity heterogeneity but not in patients with WMD.